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Carnegie Mellon University Guidelines for Design and Construction Last updated September 5, 2008 9:14 AM The purpose of this document is to provide Project Managers with an overview of environmental, health and safety issues as they relate the design and construction of experimental research laboratories. The guidelines presented here are for non-specialized laboratories using the following hazards:
These guidelines do not preclude involving the Environmental Health & Safety office but should serve as points of discussion with researchers. Biosafety Containment Laboratories Construction of Biosafety Containment Laboratories (Revised /2007) The purpose of this document is to aid project managers and Principal Investigators in the design and construction of biosafety containment laboratories. The guidelines presented here are for general use Biological Safety Level 1 and 2 containment laboratories. These guidelines comply with all requirements specified in the Centers for Disease Control and Prevention’s/National Institute of Health’s publication, Biosafety in Microbiological and Biomedical Laboratories and NIH’s Guidelines for Research Involving Recombinant DNA Molecules. If vertebrate animals are involved in research with biohazardous materials, special precautions are required. Requirements will be specified on a case-by-case basis by EH&S personnel. Basic Laboratory Design for Biological Safety Level 1 (BSL-1) Containment
Basic Laboratory Design for Biological Safety Level 2 (BSL-2) Containment In addition to the requirements for a BSL-1 laboratory, the following are required:
References
Class IV Laser Laboratories (Revised 3/2007) The purpose of this document is to aid Project Designers and Principal Investigators in the design and construction of Class IV laser laboratories. These guidelines comply with all requirements specified in the latest edition of ANSI Z136.1, American National Standard for Safe Use of Lasers. The final design for Class IV laser laboratories at Carnegie Mellon University will be determined through a review of proposed laser usage involving the responsible Principal Investigator (PI), the Project Manager and the Carnegie Mellon University Laser Safety Officer (LSO), who resides in the Carnegie Mellon University Department of Environmental Health and Safety. The LSO will need to approve final design. In some cases, laser lab design determined by the LSO and PI will deviate from this specification to achieve the best mix of safety and flexibility / efficiency for the principal investigator. For this reason, it is strongly recommended that laser design discussions be held early in the design process with participation from the Principal investigator, the Project Manager and the Carnegie Mellon University laser safety officer (LSO). Please contact the Carnegie Mellon University Laser Safety Officers (Mark Banister at (412)268-1493 or Andrew Lawson at (412)268-8405) for any questions regarding these guidelines. Signage Entryways into the laser usage area shall have signs that alert personnel to the type(s) of laser(s) that may be encountered within that particular lab. A list of authorized users and emergency contact numbers should also be provided on this sign. This is typically a laminated sheet attached to the door. In addition, an ANSI compliant illuminated laser warning sign (Figures 1 and 2) shall be mounted above the entryway to the lab and shall be illuminated whenever the laser is energized and capable of producing a beam. This sign contains the following warning: DANGER Figure 1-Illuminated Laser Signs
Figure 2-Preferred Type
 Please contact the Carnegie Mellon University Laser Safety Officer for details on the preferred equipment.
Figure 3-Cipher Lock with Key Override
Laser Beam Containment Curtain If the curtain is parted wide enough, however, (e.g. for equipment access) an interlock (Figures 5 and 6) sewn into the curtain shall activate and the laser(s) will be de-energized. Figure 4- Laser Containment Curtain on Track  
Figure 5-Pull-Apart Interlock Switch Figure
6-Interlock Shown Installed on Curtain
Control Circuit
Laboratory Layout Figure 7-Layout of Class IV Laser Laboratory
Figure 8-Eyewear Station
An emergency laser beam off switch (Figure 9) is located just inside the door, as shown, and is available to emergency responders to cease laser beam operation before entry. A second laser stop switch may be located in the laser usage area and be available to lab occupants.
Figure 9-Emergency Laser & Power Kill Mushroom type buttons
The curtain is parted and the user may enter the laser usage area via the curtain overlap without breaking the pull-apart interlock. A secondary exit may be equipped with a "hard interlock" as shown in Figure 7. This switch action will cease laser operation when the door is opened and can not be defeated. Within the lab are located the start / stop controls for the laser power supply which are wired similar to the supplied schematic. Refer to the circuit description in the previous section. Window panels in doors should be covered or replaced with an opaque material. In general, windows in the laboratory are covered both for light level control and to contain stray beams so that they are not reflected outside. All class IV laser labs should be equipped with smoke detectors, sprinkler heads, and fire alarm annunciators. Gases required for excimer lasers may require gas cabinets with adequate exhaust and an exhaust monitoring device, additional sprinkler heads, and a gas detection system wired for fail-safe shutdown. Contact the Laser Safety Officers for specific details of these controls.
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